Characterizing novel proteins involved in DNA damage and immune signaling pathways using cell
biology and biochemistry techniques (CRISPR, RNAi, western blotting, immunofluorescence,
immunoprecipitation, chromatography, flow cytometry, and reporter gene assays).
Performing standard molecular biology techniques (cloning, site-directed mutagenesis, production
and purification of recombinant proteins).
Performing tissue culture work doing plasmid transfection, retroviral transduction, and lentiviral
Assisting in CRISPR functional genomic screen to identify genes required for the selective survival
of tumor cells with specific DNA repair or immune signaling defects
Assisting with quantitative mass spectrometry proteomics to characterize novel post-translational
modifications involved in the DNA damage response.
Assisting with cancer gene mouse model.
Establishing new and modify existing research techniques.
Bachelor degree in biology, biochemistry, chemistry, biotechnology or related science field
1-3 years experience in a molecular laboratory a plus
Full-time, between May and August 2021